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EUbOPEN wave 1

This submission holds the raw data and processed images for a high-content live-cell multiplex screen. The screen is used for chemogenomic compounnd annotation, i.e. the evaluation of e.g. cytotoxic effects. This submission is about a set of >550 chemogenomic candidate compounds, tested in a pre-screen and a primary screen. Further information about the EUbOPEN project, from which this set and experiment originated can be found in the links section.

HSCSP-COVIRNA

TOCOVID

IL-2 Hepatotox-Cohort

In vitro assays to identify IL-2 mediated hepatotoxicity

IMIDIA Cohort 1

IMIDIA Cohort 2

IMIDIA Cohort 3

Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR

Understanding the influence of genetic variants on DNA methylation is fundamental for the interpretation of epigenomic data in the context of disease. The dataset developed in this project provides matched genotyping and DNA methylation data in four tissues (ileum, rectum, T-cells, B-cells) from healthy individuals. Using this data, we demonstrate the discrimination of common from cell-type-specific methQTLs. Our analysis demonstrates that a systematic analysis of methQTLs provides important ...

ImmUniverse DPP Cohort (AD/UC)

The ImmUniverse Deep Personal Profiling (DPP) cohort is part of the ImmUniverse project and contains Atopic Dermatitis (AD) and Ulcerative Colitis (UC) patients. It involves deep personal profiling of patients through extensive clinical data, multi-modal sampling (blood and tissue), and multi-omics layers to support precision medicine approaches and disease stratification. Longitudinal study, atopic dermatitis, ulcerative colitis, immune-mediated inflammatory diseases, deep personal profiling...