Study

U-BIOPRED

dc9aa634-147a-11eb-b51f-8c8590c45a21

A observational study of people with mild, moderate and severe asthma including both smokers and non-smokers and a control group of healthy volunteers. An extensive range of clinical parameters and omics from blood, urine, sputum and bronchial brushings and biopsy and nasal brushings.

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  1. U-BIOPRED

Study description
Primary purpose
Phenotype severe asthma
Description of cohorts
Cohort A adult: Severe asthma non-smoking (under 5 pack years). Cohort B Adult: Severe asthma smoking (5+ pack years). Cohort C Adult: Mild-moderate asthma. Cohort D adult: Healthy volunteers. Cohort A Paediatric: Severe school aged asthma. Cohort B Paediatric: Mild-moderate school aged asthma. Cohort C Paediatric: Severe pre-school aged asthma/wheeze. Cohort D Paediatric: Mild-moderate pre-school aged asthma/wheeze. Adult: Cohort A: 367, Cohort B: 121, Cohort C: 130, Cohort D: 112, Paediatric Cohort A: 102, Cohort B: 58, Cohort C: 83, Cohort D: 56.

Subjects
Number of subjects
1025
Sample sources
tissue sample
Samples collected
lung

Demographic and participant information
Cohort characteristics
BMI 17.77-53.63
age at enrollment 1-79 year