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8 studies found

IL-2 Hepatotox-Cohort

In vitro assays to identify IL-2 mediated hepatotoxicity

Types In Vitro Assays
TEST-4-D3F6E0-1

LuxPark

The cohort includes people with Parkinson’s disease, atypical parkinsonism, and healthy controls, who have their state of health regularly monitored by specialists over many years. The participants donate samples of body fluids such as blood or urine. They also take part in clinical examinations that analyze movement sequences and test their attention, memory, vision, speech, and sense of smell.

Types Clinical Trial Ncit:c71104
ELU-4-F67092-1

PEI HUVEC-characterization study

Within a broad characterization study, we analyzed activation, viability, cytokine secretion, and permeability of human umbilical vein endothelial cells (HUVECs) upon stimulation with different stimuli. In addition HUVEC-permeability was analyzed in a trans-well-based leakage assay upon stimulation in presence or absence of human peripheral blood mononuclear cells (PBMCs).

Types In Vitro Study
ELU-4-4238C7-1

PRECISESADS: Cross Sectional Study & Inception Cohort

The goal of this project is to use the power of OMICs, and bioinformatics to identify new classifications for diseases known to share common pathophysiological mechanisms. Such knowledge has not been applied to individual patients, depriving them of potential benefits in terms of the use of new therapeutic agents that are being developed for one disease but cannot be applied in another, due to current clinical classifications. We will investigate individuals with systemic lupus erythematosus ...

Types Observational
ELU-4-9E5405-1

Pfizer (NCT02958865)

The Pfizer UC dataset represents baseline, placebo and treatment (PF-06700841) subject and sample-level data extracted from a phase 2 study in moderate to severe ulcerative colitis.

Types Clinical Trial Ncit:c71104 Nct02958865
ELU-4-B16B4B-1