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194 projects found

NCER-PD - National Centre of Excellence in Research for Parkin...
ELU-1-658866-1

We currently do not know enough about Parkinson's disease. We are still far from understanding the relationship between the different symptoms and it is still a mystery why some people are affected and others not. In addition, the disease progression, whether it is slow or fast, cannot be predicted at the moment. As the causes of Parkinson's disease are still unknown, new research projects are necessary that give us new ways for prevention, diagnosis and treatment. The NCER-PD research team, ...

Keywords: Parkinson's disease neurological disorder Atypical Parkinson Cognitive data Imaging data Parkison's disease motor symptoms

NeuroDeRisk
f308e53e-5f11-11eb-917b-acde48001122

Neurotoxicity de-risking in preclinical drug discovery

Keywords: IMI projects Tools for predicting/monitoring safety 3Rs - animal use in research

MiBiPa - Non-invasive microbiome-derived multi-omic biomarker...
ELU-1-913FE2-1

Parkinson’s disease (PD) research benefits from knowledge of disease-specific risk and resilience factors and elucidation of pathophysiological concepts on the emergence of neurodegeneration. Presently the propagation of a-synuclein aggregation in PD is proposed to start in the periphery, i.e. in the enteric nervous system and the olfactory bulb. Aberrations within the gastrointestinal and nasal microbiomes may play a role in the initiation of this process. This is of particular relevance in...

Keywords: Parkinson’s disease microbiome biomarker

ORBITO
f3f10c06-5f11-11eb-917b-acde48001122

Oral biopharmaceutics tools

Keywords: IMI projects Tools for predicting/monitoring safety Drug delivery

OncoTrack
dc9c45f2-147a-11eb-b51f-8c8590c45a21

Methods for systematic next generation oncology biomarker development

Keywords: IMI projects Translational Medicine Cancer Tools for predicting/monitoring safety

fairplus stamp

Open PHACTS
f31a26c8-5f11-11eb-917b-acde48001122

The Open Pharmacological Concepts Triple Store

Keywords: IMI projects Big data and knowledge management Drug discovery

optima - Optima
9d2aca6a-ac64-4c38-a86c-8ef971f1288f

Optimal treatment for patients with solid tumours in Europe through artificial intelligence

Keywords: IMI projects IMI2 Cancer Real-world data Evidence Artificial intelligence

PARADIGM
f2435ddc-5f11-11eb-917b-acde48001122

Patients active in research and dialogues for an improved generation of medicines: advancing meaningful patient engagement in the life cycle of medicines for better health outcomes

Keywords: IMI projects Clinical trial design Patient involvement in R&D Regulatory and HTA processes