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185 projects found

imSAVAR · Immune safety avatar: nonclinical mimicking of the immune system effects of immunomodulatory therapies

Certain treatments for cancers and autoimmune diseases work by altering the immune system. However, a major challenge for researchers is identifying potential efficacy and safety issues with these treatments early in drug development, before they are tested in humans. Part of the problem is that the tests used early in drug development do not reflect the full complexity of the human immune system. In addition, these tests tend to be based on a healthy immune system, which is different to the ...

Keywords IMI projects Immunology Autoimmune diseases Tools for predicting/monitoring efficacy Tools for predicting/monitoring safety
Started
2019-12-01
ELU-1-D00FB4-1

Immune-Image

Specific imaging of immune cell dynamics using novel tracer strategies

Keywords IMI projects Biologicals Imaging
Started
2019-10-01
f3e46c44-5f11-11eb-917b-acde48001122

Impentri

Development of Impentri, an intravenous imatinib formulation for COVID-19 acute respiratory distress syndrome (ARDS)

Keywords IMI projects Respiratory diseases Infectious diseases Coronaviruses Conducting clinical trials
Started
2020-07-01
f1a56a78-5f11-11eb-917b-acde48001122

inno4vac · Inno4vac

Innovations to accelerate vaccine development and manufacture

Keywords IMI projects IMI2 Vaccines Tools for predicting/monitoring efficacy Big data and knowledge management Artificial intelligence
Started
2021-09-01
a6401913-3453-45ab-a537-46808e1d7578

K4DD

Kinetics for Drug Discovery

Keywords IMI projects Tools for predicting/monitoring efficacy Tools for predicting/monitoring safety Drug discovery
Started
2012-11-01
f18682f2-5f11-11eb-917b-acde48001122

KRONO

Evaluation of a production ready portable, point-of-need platform (instrument and reagents), direct from nasal swab test for the molecular diagnostic detection of COVID-19 infection

Keywords IMI projects Respiratory diseases Infectious diseases Coronaviruses Diagnostics
Started
2020-09-01
f0157202-5f11-11eb-917b-acde48001122

LITMUS

Liver Investigation: Testing Marker Utility in Steatohepatitis

Keywords IMI projects Diabetes & metabolic disorders Diagnostics Tools for predicting/monitoring efficacy Disease taxonomy
Started
2017-11-01
f3639baa-5f11-11eb-917b-acde48001122

MACUSTAR

Intermediate AMD: development of novel clinical endpoints for clinical trials in patients with a regulatory and patient access intention

Keywords IMI projects Ageing-associated diseases Eye diseases Tools for predicting/monitoring efficacy Patient involvement in R&D Imaging
Started
2017-09-01
f728a46a-5f11-11eb-917b-acde48001122