ENABLE
European Gram-negative Antibacterial Engine
- Started
- 2014-02-01
- Website
- http://nd4bb-enable.eu/
European Gram-negative Antibacterial Engine
European regimen accelerator for tuberculosis
Novel Gram-negative antibiotic now
New Drugs for Bad Bugs. Umbrella programme comprising the IMI projects TRANSLOCATION, ENABLE, COMBACTE-NET, COMBACTE-CARE, COMBACTE-MAGNET, COMBACTE-CDI, iABC and DRIVE-AB
Predicting the impact of monoclonal antibodies & vaccines on antimicrobial resistance
Progress novel assets (one FIH start) for non-tubercular mycobacteria that may act synergistically with bedaquiline and cytochrome bc drugs
Progress new assets (one pre-new molecular entity and one first-time-in-human start) for tuberculosis that act synergistically with bedaquiline, cytochrome bc or cytochrome bd inhibitors
Molecular basis of the bacterial cell wall permeability