{
  "@context": [
    "https://w3id.org/dats/context/sdo/dataset_sdo_context.jsonld",
    "http://w3id.org/dats/context/obo/dataset_obo_context.jsonld"
  ],
  "@type": "Project",
  "acronym": "covirna",
  "description": "A diagnostic test to improve surveillance and care of COVID-19 patients",
  "endDate": {
    "@context": "https://w3id.org/dats/context/sdo/date_info_sdo_context.jsonld",
    "@type": "Date",
    "date": "Mon, 31 Oct 2022 00:00:00 GMT",
    "type": {
      "value": "end date",
      "valueIRI": "http://semanticscience.org/resource/SIO_000036"
    }
  },
  "extraProperties": [
    {
      "category": "website",
      "values": [
        {
          "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
          "@type": "Annotation",
          "value": "https://covirna.eu/"
        }
      ]
    }
  ],
  "identifier": {
    "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
    "@type": "Identifier",
    "identifier": "07a1b414-d9b7-11eb-b117-d0577bab103e"
  },
  "keywords": [
    {
      "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
      "@type": "Annotation",
      "value": "H2020"
    }
  ],
  "projectAssets": [
    {
      "@context": "https://w3id.org/dats/context/sdo/study_sdo_context.jsonld",
      "@type": "Study",
      "acronym": "LIH-PREDI-COVID",
      "characteristics": [
        {
          "@context": "https://w3id.org/dats/context/sdo/dimension_sdo_context.jsonld",
          "@type": "Dimension",
          "identifier": {
            "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
            "@type": "Identifier",
            "identifier": "NCIT:C93599",
            "identifierSource": "NCIt"
          },
          "name": {
            "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
            "@type": "Annotation",
            "value": "Multi-institution Indicator"
          },
          "values": [
            {
              "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
              "@type": "Annotation",
              "value": "True"
            }
          ]
        }
      ],
      "description": "PREDI-COVID participants` samples and data for COVIRNA",
      "identifier": {
        "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
        "@type": "Identifier",
        "identifier": "e6f84ce3-04f3-11ec-a683-d0577bab103e"
      },
      "input": [
        {
          "@context": "https://w3id.org/dats/context/sdo/material_sdo_context.jsonld",
          "@type": "Material",
          "bearerOfDisease": [
            {
              "@context": "https://w3id.org/dats/context/sdo/disease_sdo_context.jsonld",
              "@type": "Disease",
              "name": "COVID-19"
            }
          ],
          "derivesFrom": [
            {
              "@context": "https://w3id.org/dats/context/sdo/anatomical_part_sdo_context.jsonld",
              "@type": "AnatomicalPart",
              "name": "plasma"
            }
          ],
          "name": "input material",
          "taxonomy": [
            {
              "@context": "https://w3id.org/dats/context/sdo/taxonomic_info_sdo_context.jsonld",
              "@type": "TaxonomicInformation",
              "name": "Homo sapiens"
            }
          ]
        }
      ],
      "name": "the samples to be used within COVIRNA were collected as part of the clinical study registered with the \"ClinicalTrials.gov Identifier: NCT04332094\". Randomized Interventional Pilot Phase II Clinical Trial;  SARS-CoV-2 infection; Primary outcomes: mechanical ventilation, In-hospital mortality.",
      "output": [
        {
          "@context": "https://w3id.org/dats/context/sdo/dataset_sdo_context.jsonld",
          "@type": "Dataset",
          "creators": [
            {
              "@context": "https://w3id.org/dats/context/sdo/organization_sdo_context.jsonld",
              "@type": "Organization",
              "name": ""
            }
          ],
          "dimensions": [
            {
              "@context": "http://w3id.org/dats/context/obo/category_values_pair_obo_context.jsonld",
              "@type": "Dimension",
              "name": {
                "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
                "@type": "Annotation",
                "value": "sample size",
                "valueIRI": "NCIT:C53190"
              },
              "values": [
                {
                  "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
                  "@type": "Annotation",
                  "value": "167"
                }
              ]
            }
          ],
          "distributions": [
            {
              "@context": "https://w3id.org/dats/context/sdo/dataset_distribution_sdo_context.jsonld",
              "@type": "DatasetDistribution",
              "access": {
                "@context": "https://w3id.org/dats/context/sdo/access_sdo_context.jsonld",
                "@type": "Access",
                "accessURL": "",
                "landingPage": "COVIRNA restricted data, FAIRifed v1"
              },
              "dates": [
                {
                  "@context": "https://w3id.org/dats/context/sdo/date_info_sdo_context.jsonld",
                  "@type": "Date",
                  "date": "Sun, 01 Nov 2020 11:59:59 GMT",
                  "type": {
                    "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
                    "@type": "Annotation",
                    "value": "creation date"
                  }
                }
              ],
              "version": "V1.0"
            }
          ],
          "identifier": {
            "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
            "@type": "Identifier",
            "identifier": "e6f84ce4-04f3-11ec-95a4-d0577bab103e"
          },
          "isAbout": [
            {
              "@context": "https://w3id.org/dats/context/sdo/disease_sdo_context.jsonld",
              "@type": "Disease",
              "name": "COVID-19"
            }
          ],
          "title": "LIH-PREDI-COVID",
          "types": [
            {
              "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
              "@type": "Annotation",
              "value": "lncRNA sequencing"
            }
          ]
        }
      ],
      "studyGroups": [
        {
          "@context": "https://w3id.org/dats/context/sdo/studygroup_sdo_context.jsonld",
          "@type": "StudyGroup",
          "consentInformation": [
            {
              "@context": "https://w3id.org/dats/context/sdo/consent_info_obo_context.jsonld",
              "@type": "ConsentInfo",
              "identifier": {
                "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
                "@type": "Identifier",
                "identifier": "NCIT:C16735",
                "identifierSource": "NCIt"
              },
              "name": {
                "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
                "@type": "Annotation",
                "value": "Informed Consent"
              }
            }
          ],
          "name": "COVID-19 infected patients with various degrees of severity from Luxembourg.",
          "size": 167
        }
      ],
      "types": [
        {
          "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
          "@type": "Annotation",
          "value": "PREDI-COVID participants` samples and data for COVIRNA"
        }
      ]
    },
    {
      "@context": "https://w3id.org/dats/context/sdo/study_sdo_context.jsonld",
      "@type": "Study",
      "acronym": "UDUS-MiRCOVID",
      "characteristics": [
        {
          "@context": "https://w3id.org/dats/context/sdo/dimension_sdo_context.jsonld",
          "@type": "Dimension",
          "identifier": {
            "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
            "@type": "Identifier",
            "identifier": "NCIT:C93599",
            "identifierSource": "NCIt"
          },
          "name": {
            "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
            "@type": "Annotation",
            "value": "Multi-institution Indicator"
          },
          "values": [
            {
              "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
              "@type": "Annotation",
              "value": "True"
            }
          ]
        }
      ],
      "description": "MiRCOVID participants` samples and data for COVIRNA",
      "identifier": {
        "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
        "@type": "Identifier",
        "identifier": "e6f87413-04f3-11ec-8af3-d0577bab103e"
      },
      "input": [
        {
          "@context": "https://w3id.org/dats/context/sdo/material_sdo_context.jsonld",
          "@type": "Material",
          "bearerOfDisease": [
            {
              "@context": "https://w3id.org/dats/context/sdo/disease_sdo_context.jsonld",
              "@type": "Disease",
              "name": "COVID-19"
            }
          ],
          "derivesFrom": [
            {
              "@context": "https://w3id.org/dats/context/sdo/anatomical_part_sdo_context.jsonld",
              "@type": "AnatomicalPart",
              "name": "plasma"
            }
          ],
          "name": "input material",
          "taxonomy": [
            {
              "@context": "https://w3id.org/dats/context/sdo/taxonomic_info_sdo_context.jsonld",
              "@type": "TaxonomicInformation",
              "name": "Homo sapiens"
            }
          ]
        }
      ],
      "name": "The study aims to evaluate the involvement of microRNAs in severe COVID-19. Plasma and urine samples is collected at 5 different time points. MicroRNA levels are analyzed and compared in severely ill COVID patients with regard in acute kidney injury and heart failure.",
      "output": [
        {
          "@context": "https://w3id.org/dats/context/sdo/dataset_sdo_context.jsonld",
          "@type": "Dataset",
          "creators": [
            {
              "@context": "https://w3id.org/dats/context/sdo/organization_sdo_context.jsonld",
              "@type": "Organization",
              "name": ""
            }
          ],
          "dimensions": [
            {
              "@context": "http://w3id.org/dats/context/obo/category_values_pair_obo_context.jsonld",
              "@type": "Dimension",
              "name": {
                "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
                "@type": "Annotation",
                "value": "sample size",
                "valueIRI": "NCIT:C53190"
              },
              "values": [
                {
                  "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
                  "@type": "Annotation",
                  "value": "~200"
                }
              ]
            }
          ],
          "distributions": [
            {
              "@context": "https://w3id.org/dats/context/sdo/dataset_distribution_sdo_context.jsonld",
              "@type": "DatasetDistribution",
              "access": {
                "@context": "https://w3id.org/dats/context/sdo/access_sdo_context.jsonld",
                "@type": "Access",
                "accessURL": "",
                "landingPage": "COVIRNA restricted data, FAIRifed v1"
              },
              "dates": [
                {
                  "@context": "https://w3id.org/dats/context/sdo/date_info_sdo_context.jsonld",
                  "@type": "Date",
                  "date": "Sun, 01 Nov 2020 11:59:59 GMT",
                  "type": {
                    "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
                    "@type": "Annotation",
                    "value": "creation date"
                  }
                }
              ],
              "version": "V1.0"
            }
          ],
          "identifier": {
            "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
            "@type": "Identifier",
            "identifier": "e6f87414-04f3-11ec-b012-d0577bab103e"
          },
          "isAbout": [
            {
              "@context": "https://w3id.org/dats/context/sdo/disease_sdo_context.jsonld",
              "@type": "Disease",
              "name": "COVID-19"
            }
          ],
          "title": "UDUS-MiRCOVID",
          "types": [
            {
              "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
              "@type": "Annotation",
              "value": "lncRNA sequencing"
            }
          ]
        }
      ],
      "studyGroups": [
        {
          "@context": "https://w3id.org/dats/context/sdo/studygroup_sdo_context.jsonld",
          "@type": "StudyGroup",
          "consentInformation": [
            {
              "@context": "https://w3id.org/dats/context/sdo/consent_info_obo_context.jsonld",
              "@type": "ConsentInfo",
              "identifier": {
                "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
                "@type": "Identifier",
                "identifier": "NCIT:C16735",
                "identifierSource": "NCIt"
              },
              "name": {
                "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
                "@type": "Annotation",
                "value": "Informed Consent"
              }
            }
          ],
          "name": "UDUS cohort of positive patients for COVID-19: a stratification study evaluating the involvement of microRNAs in severe COVID-19.",
          "size": 50
        }
      ],
      "types": [
        {
          "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
          "@type": "Annotation",
          "value": "MiRCOVID participants` samples and data for COVIRNA"
        }
      ]
    },
    {
      "@context": "https://w3id.org/dats/context/sdo/study_sdo_context.jsonld",
      "@type": "Study",
      "acronym": "PSD-COVID19-OMICS",
      "characteristics": [
        {
          "@context": "https://w3id.org/dats/context/sdo/dimension_sdo_context.jsonld",
          "@type": "Dimension",
          "identifier": {
            "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
            "@type": "Identifier",
            "identifier": "NCIT:C93599",
            "identifierSource": "NCIt"
          },
          "name": {
            "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
            "@type": "Annotation",
            "value": "Multi-institution Indicator"
          },
          "values": [
            {
              "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
              "@type": "Annotation",
              "value": "True"
            }
          ]
        }
      ],
      "description": "PSD COVID19 OMICS",
      "identifier": {
        "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
        "@type": "Identifier",
        "identifier": "e6f87415-04f3-11ec-96d0-d0577bab103e"
      },
      "input": [
        {
          "@context": "https://w3id.org/dats/context/sdo/material_sdo_context.jsonld",
          "@type": "Material",
          "bearerOfDisease": [
            {
              "@context": "https://w3id.org/dats/context/sdo/disease_sdo_context.jsonld",
              "@type": "Disease",
              "name": "COVID-19"
            }
          ],
          "derivesFrom": [
            {
              "@context": "https://w3id.org/dats/context/sdo/anatomical_part_sdo_context.jsonld",
              "@type": "AnatomicalPart",
              "name": "plasma"
            }
          ],
          "name": "input material",
          "taxonomy": [
            {
              "@context": "https://w3id.org/dats/context/sdo/taxonomic_info_sdo_context.jsonld",
              "@type": "TaxonomicInformation",
              "name": "Homo sapiens"
            }
          ]
        }
      ],
      "name": "COVIRNA  is part of COVID19_OMICS which is an observational, prospective study conducted by IRCCS Policlinico San Donato that provides the evaluation of circulating biomarkers predicting the clinical evolution in patients with COVID-19.",
      "output": [
        {
          "@context": "https://w3id.org/dats/context/sdo/dataset_sdo_context.jsonld",
          "@type": "Dataset",
          "creators": [
            {
              "@context": "https://w3id.org/dats/context/sdo/organization_sdo_context.jsonld",
              "@type": "Organization",
              "name": ""
            }
          ],
          "dimensions": [
            {
              "@context": "http://w3id.org/dats/context/obo/category_values_pair_obo_context.jsonld",
              "@type": "Dimension",
              "name": {
                "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
                "@type": "Annotation",
                "value": "sample size",
                "valueIRI": "NCIT:C53190"
              },
              "values": [
                {
                  "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
                  "@type": "Annotation",
                  "value": "~200"
                }
              ]
            }
          ],
          "distributions": [
            {
              "@context": "https://w3id.org/dats/context/sdo/dataset_distribution_sdo_context.jsonld",
              "@type": "DatasetDistribution",
              "access": {
                "@context": "https://w3id.org/dats/context/sdo/access_sdo_context.jsonld",
                "@type": "Access",
                "accessURL": "",
                "landingPage": "COVIRNA restricted data, FAIRifed v1"
              },
              "dates": [
                {
                  "@context": "https://w3id.org/dats/context/sdo/date_info_sdo_context.jsonld",
                  "@type": "Date",
                  "date": "Sun, 01 Nov 2020 11:59:59 GMT",
                  "type": {
                    "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
                    "@type": "Annotation",
                    "value": "creation date"
                  }
                }
              ],
              "version": "V1.0"
            }
          ],
          "identifier": {
            "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
            "@type": "Identifier",
            "identifier": "e6f87416-04f3-11ec-b619-d0577bab103e"
          },
          "isAbout": [
            {
              "@context": "https://w3id.org/dats/context/sdo/disease_sdo_context.jsonld",
              "@type": "Disease",
              "name": "COVID-19"
            }
          ],
          "title": "PSD-COVID19-OMICS",
          "types": [
            {
              "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
              "@type": "Annotation",
              "value": "lncRNA sequencing"
            }
          ]
        }
      ],
      "studyGroups": [
        {
          "@context": "https://w3id.org/dats/context/sdo/studygroup_sdo_context.jsonld",
          "@type": "StudyGroup",
          "consentInformation": [
            {
              "@context": "https://w3id.org/dats/context/sdo/consent_info_obo_context.jsonld",
              "@type": "ConsentInfo",
              "identifier": {
                "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
                "@type": "Identifier",
                "identifier": "NCIT:C16735",
                "identifierSource": "NCIt"
              },
              "name": {
                "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
                "@type": "Annotation",
                "value": "Informed Consent"
              }
            }
          ],
          "name": "PSD unit has been recruiting COVID-19 patients starting from March 2019 during the first pandemic outbreak. Patients were admitted to the COVID-19 ward or to intensive care units and blood was harvested within 7 days after admission. Samples were processed, divided in aliquots and stored at -80 \u00b0C in the PSD biobank according to BMRI guidelines. The Biobank also keep record of the signed patient consensus forms. Platelet poor plasma (PPP) samples were then transferred to Firalis. Sample/data couples were anonymized before shipping. The cohort main characteristics are: 63% males, age 67.74\u00b111.49 (median years\u00b1SD), 40% intubated, 25% required O2 therapy, 24% CPAP in ward; 11% displayed mild disease, 25% died and 75% were eventually discharged. The main comorbidities were: T2DM 20%, obesity 19% and hypertension 54% of the cases . ",
          "size": 100
        }
      ],
      "types": [
        {
          "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
          "@type": "Annotation",
          "value": "PSD COVID19 OMICS"
        }
      ]
    },
    {
      "@context": "https://w3id.org/dats/context/sdo/study_sdo_context.jsonld",
      "@type": "Study",
      "acronym": "ULEI-PROVID-PROGRESS-1",
      "characteristics": [
        {
          "@context": "https://w3id.org/dats/context/sdo/dimension_sdo_context.jsonld",
          "@type": "Dimension",
          "identifier": {
            "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
            "@type": "Identifier",
            "identifier": "NCIT:C93599",
            "identifierSource": "NCIt"
          },
          "name": {
            "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
            "@type": "Annotation",
            "value": "Multi-institution Indicator"
          },
          "values": [
            {
              "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
              "@type": "Annotation",
              "value": "True"
            }
          ]
        }
      ],
      "description": "PROVID cohort of hospitalized COVID-19 patients",
      "identifier": {
        "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
        "@type": "Identifier",
        "identifier": "e6f87417-04f3-11ec-a738-d0577bab103e"
      },
      "input": [
        {
          "@context": "https://w3id.org/dats/context/sdo/material_sdo_context.jsonld",
          "@type": "Material",
          "bearerOfDisease": [
            {
              "@context": "https://w3id.org/dats/context/sdo/disease_sdo_context.jsonld",
              "@type": "Disease",
              "name": "COVID-19"
            }
          ],
          "derivesFrom": [
            {
              "@context": "https://w3id.org/dats/context/sdo/anatomical_part_sdo_context.jsonld",
              "@type": "AnatomicalPart",
              "name": "plasma"
            }
          ],
          "name": "input material",
          "taxonomy": [
            {
              "@context": "https://w3id.org/dats/context/sdo/taxonomic_info_sdo_context.jsonld",
              "@type": "TaxonomicInformation",
              "name": "Homo sapiens"
            }
          ]
        }
      ],
      "name": "U07.1! , COVID-19, SARS-CoV-2 infection, prospective, longitudinal, observational, multi-center, medical history, clinical characteristics, laboratory parameters, quality of life, mechanical ventilation, medication, treatments",
      "studyGroups": [
        {
          "@context": "https://w3id.org/dats/context/sdo/studygroup_sdo_context.jsonld",
          "@type": "StudyGroup",
          "consentInformation": [
            {
              "@context": "https://w3id.org/dats/context/sdo/consent_info_obo_context.jsonld",
              "@type": "ConsentInfo",
              "identifier": {
                "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
                "@type": "Identifier",
                "identifier": "NCIT:C16735",
                "identifierSource": "NCIt"
              },
              "name": {
                "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
                "@type": "Annotation",
                "value": "Informed Consent"
              }
            }
          ],
          "name": "The PROVID-PROGRESS Study is a prospective, longitudinal, observational, multi-center study of hospitalized Patients positive for SARS-CoV-2 with the aim to identify clinical and molecular markers of disease progression and new therapies."
        }
      ],
      "types": [
        {
          "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
          "@type": "Annotation",
          "value": "PROVID cohort of hospitalized COVID-19 patients"
        }
      ]
    },
    {
      "@context": "https://w3id.org/dats/context/sdo/study_sdo_context.jsonld",
      "@type": "Study",
      "acronym": "ULEI-PROVID-CAPNETZ-2",
      "characteristics": [
        {
          "@context": "https://w3id.org/dats/context/sdo/dimension_sdo_context.jsonld",
          "@type": "Dimension",
          "identifier": {
            "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
            "@type": "Identifier",
            "identifier": "NCIT:C93599",
            "identifierSource": "NCIt"
          },
          "name": {
            "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
            "@type": "Annotation",
            "value": "Multi-institution Indicator"
          },
          "values": [
            {
              "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
              "@type": "Annotation",
              "value": "True"
            }
          ]
        }
      ],
      "description": "PROVID cohort of hospitalized COVID-19 patients",
      "identifier": {
        "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
        "@type": "Identifier",
        "identifier": "e6f87419-04f3-11ec-a27b-d0577bab103e"
      },
      "input": [
        {
          "@context": "https://w3id.org/dats/context/sdo/material_sdo_context.jsonld",
          "@type": "Material",
          "bearerOfDisease": [
            {
              "@context": "https://w3id.org/dats/context/sdo/disease_sdo_context.jsonld",
              "@type": "Disease",
              "name": "COVID-19"
            }
          ],
          "derivesFrom": [
            {
              "@context": "https://w3id.org/dats/context/sdo/anatomical_part_sdo_context.jsonld",
              "@type": "AnatomicalPart",
              "name": "plasma"
            }
          ],
          "name": "input material",
          "taxonomy": [
            {
              "@context": "https://w3id.org/dats/context/sdo/taxonomic_info_sdo_context.jsonld",
              "@type": "TaxonomicInformation",
              "name": "Homo sapiens"
            }
          ]
        }
      ],
      "name": "U07.1! , COVID-19, SARS-CoV-2 infection, prospective, longitudinal, observational, multi-center, medical history, clinical characteristics, laboratory parameters, quality of life, mechanical ventilation, medication, treatments",
      "studyGroups": [
        {
          "@context": "https://w3id.org/dats/context/sdo/studygroup_sdo_context.jsonld",
          "@type": "StudyGroup",
          "consentInformation": [
            {
              "@context": "https://w3id.org/dats/context/sdo/consent_info_obo_context.jsonld",
              "@type": "ConsentInfo",
              "identifier": {
                "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
                "@type": "Identifier",
                "identifier": "NCIT:C16735",
                "identifierSource": "NCIt"
              },
              "name": {
                "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
                "@type": "Annotation",
                "value": "Informed Consent"
              }
            }
          ],
          "name": "The PROVID-CAPNETZ Study is a prospective, longitudinal, observational, multi-center study of hospitalized Patients positive for SARS-CoV-2 with the aim to identify clinical and molecular markers of disease progression and new therapies."
        }
      ],
      "types": [
        {
          "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
          "@type": "Annotation",
          "value": "PROVID cohort of hospitalized COVID-19 patients"
        }
      ]
    },
    {
      "@context": "https://w3id.org/dats/context/sdo/study_sdo_context.jsonld",
      "@type": "Study",
      "acronym": "HSCSP-COVIRNA",
      "characteristics": [
        {
          "@context": "https://w3id.org/dats/context/sdo/dimension_sdo_context.jsonld",
          "@type": "Dimension",
          "identifier": {
            "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
            "@type": "Identifier",
            "identifier": "NCIT:C93599",
            "identifierSource": "NCIt"
          },
          "name": {
            "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
            "@type": "Annotation",
            "value": "Multi-institution Indicator"
          },
          "values": [
            {
              "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
              "@type": "Annotation",
              "value": "True"
            }
          ]
        }
      ],
      "description": "TOCOVID",
      "identifier": {
        "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
        "@type": "Identifier",
        "identifier": "e6f8741d-04f3-11ec-a1bc-d0577bab103e"
      },
      "input": [
        {
          "@context": "https://w3id.org/dats/context/sdo/material_sdo_context.jsonld",
          "@type": "Material",
          "bearerOfDisease": [
            {
              "@context": "https://w3id.org/dats/context/sdo/disease_sdo_context.jsonld",
              "@type": "Disease",
              "name": "COVID-19"
            }
          ],
          "derivesFrom": [
            {
              "@context": "https://w3id.org/dats/context/sdo/anatomical_part_sdo_context.jsonld",
              "@type": "AnatomicalPart",
              "name": "plasma"
            }
          ],
          "name": "input material",
          "taxonomy": [
            {
              "@context": "https://w3id.org/dats/context/sdo/taxonomic_info_sdo_context.jsonld",
              "@type": "TaxonomicInformation",
              "name": "Homo sapiens"
            }
          ]
        }
      ],
      "name": "the samples to be used within COVIRNA were collected as part of the clinical study registered with the \"ClinicalTrials.gov Identifier: NCT04332094\". Randomized Interventional Pilot Phase II Clinical Trial;  SARS-CoV-2 infection; Primary outcomes: mechanical ventilation, In-hospital mortality.",
      "output": [
        {
          "@context": "https://w3id.org/dats/context/sdo/dataset_sdo_context.jsonld",
          "@type": "Dataset",
          "creators": [
            {
              "@context": "https://w3id.org/dats/context/sdo/organization_sdo_context.jsonld",
              "@type": "Organization",
              "name": ""
            }
          ],
          "dimensions": [
            {
              "@context": "http://w3id.org/dats/context/obo/category_values_pair_obo_context.jsonld",
              "@type": "Dimension",
              "name": {
                "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
                "@type": "Annotation",
                "value": "sample size",
                "valueIRI": "NCIT:C53190"
              },
              "values": [
                {
                  "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
                  "@type": "Annotation",
                  "value": "~200"
                }
              ]
            }
          ],
          "distributions": [
            {
              "@context": "https://w3id.org/dats/context/sdo/dataset_distribution_sdo_context.jsonld",
              "@type": "DatasetDistribution",
              "access": {
                "@context": "https://w3id.org/dats/context/sdo/access_sdo_context.jsonld",
                "@type": "Access",
                "accessURL": "",
                "landingPage": "COVIRNA restricted data, FAIRifed v1"
              },
              "dates": [
                {
                  "@context": "https://w3id.org/dats/context/sdo/date_info_sdo_context.jsonld",
                  "@type": "Date",
                  "date": "Sun, 01 Nov 2020 11:59:59 GMT",
                  "type": {
                    "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
                    "@type": "Annotation",
                    "value": "creation date"
                  }
                }
              ],
              "version": "V1.0"
            }
          ],
          "identifier": {
            "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
            "@type": "Identifier",
            "identifier": "e6f8741e-04f3-11ec-9af9-d0577bab103e"
          },
          "isAbout": [
            {
              "@context": "https://w3id.org/dats/context/sdo/disease_sdo_context.jsonld",
              "@type": "Disease",
              "name": "COVID-19"
            }
          ],
          "title": "HSCSP-COVIRNA",
          "types": [
            {
              "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
              "@type": "Annotation",
              "value": "lncRNA sequencing"
            }
          ]
        }
      ],
      "studyGroups": [
        {
          "@context": "https://w3id.org/dats/context/sdo/studygroup_sdo_context.jsonld",
          "@type": "StudyGroup",
          "consentInformation": [
            {
              "@context": "https://w3id.org/dats/context/sdo/consent_info_obo_context.jsonld",
              "@type": "ConsentInfo",
              "identifier": {
                "@context": "https://w3id.org/dats/context/sdo/identifier_info_sdo_context.jsonld",
                "@type": "Identifier",
                "identifier": "NCIT:C16735",
                "identifierSource": "NCIt"
              },
              "name": {
                "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
                "@type": "Annotation",
                "value": "Informed Consent"
              }
            }
          ],
          "name": "This consisted on hospitalized adults (men and women =>18 years of age at the time of inclusion in the study), who can provide written informed consent before beginning any study procedure. Confirmation of SARS-CoV-2 infection by a microbiological test performed before randomization, no longer than 72 hours. Patients were no included when presenting: comorbidities that imply a poor prognosis; pregnancy or breast-feeding; serious or active bacterial infections by pathogens other than SARS-CoV-2; immunosuppressive treatment; previous evidence of latent untreated tuberculosis.",
          "size": 124
        }
      ],
      "types": [
        {
          "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
          "@type": "Annotation",
          "value": "TOCOVID"
        }
      ]
    }
  ],
  "projectLeads": [
    {
      "@context": "https://w3id.org/dats/context/sdo/person_sdo_context.jsonld",
      "@type": "Person",
      "affiliations": [
        {
          "@context": "https://w3id.org/dats/context/sdo/organization_sdo_context.jsonld",
          "@type": "Organization",
          "location": {
            "@context": "https://w3id.org/dats/context/sdo/place_sdo_context.jsonld",
            "@type": "Place",
            "postalAddress": "-"
          },
          "name": "Luxembourg Institute of Health"
        }
      ],
      "email": "Yvan.Devaux@lih.lu",
      "firstName": "Yvan",
      "fullName": "Yvan Devaux",
      "lastName": "Devaux",
      "roles": [
        {
          "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
          "@type": "Annotation",
          "value": "Primary Study Contact"
        }
      ]
    },
    {
      "@context": "https://w3id.org/dats/context/sdo/person_sdo_context.jsonld",
      "@type": "Person",
      "affiliations": [
        {
          "@context": "https://w3id.org/dats/context/sdo/organization_sdo_context.jsonld",
          "@type": "Organization",
          "location": {
            "@context": "https://w3id.org/dats/context/sdo/place_sdo_context.jsonld",
            "@type": "Place",
            "postalAddress": "-"
          },
          "name": "Luxembourg Institute of Health"
        }
      ],
      "email": "Adriana.Voicu@lih.lu",
      "firstName": "Adriana",
      "fullName": "Adriana Voicu",
      "lastName": "Voicu",
      "roles": [
        {
          "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
          "@type": "Annotation",
          "value": "Project Manager"
        }
      ]
    }
  ],
  "projectWebsite": "https://covirna.eu/",
  "startDate": {
    "@context": "https://w3id.org/dats/context/sdo/date_info_sdo_context.jsonld",
    "@type": "Date",
    "date": "Sun, 01 Nov 2020 00:00:00 GMT",
    "type": {
      "value": "start date",
      "valueIRI": "http://semanticscience.org/resource/SIO_000031"
    }
  },
  "title": "COVIRNA",
  "types": [
    {
      "@context": "https://w3id.org/dats/context/sdo/annotation_sdo_context.jsonld",
      "@type": "Annotation",
      "value": "H2020"
    }
  ]
}
